Endocrine Abstracts

Neuroendocrine tumors (NETs) of GI tract are a heterogeneous group of neoplasms that secrete peptides and amines. Small bowel NETs originate from enterochromaffin (EC) cells and secrete chromogranin A (CgA) and serotonin (5-HT). NETs are highly vascular, a reflection of increased tumour related angiogenesis. Adenosine, the major regulator of angiogenesis, is released by enhanced degradation of ATP, during cellular stress, damage and hypoxia.Aims: Aims of...